Behavioral Neuroscience of Drug Addiction: 3 (Current Topics in Behavioral Neurosciences)

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Description

Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral keep an eye on leading to personal dev- tation. The disorder af?icts millions of people, frequently co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations is also demonstrated at the cellular, neu- transmitter, and regional levels of information processing the use of either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse all over periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that remedy options will in the end employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, a part of the Springer series on Current Topics in Behavioral Neurosciences, accommodates scholarly reviews by noted experts on a couple of topics from both basic and clinical neuroscience ?elds.

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