Intrinsic Factors: William Bosworth Castle and the Development of Hematology and Clinical Investigation at Boston City Hospital (Boston Medical Library in the Countway Library of Medicine)

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Description

Dr. W. B. Castle (1897-1990), who played an incredible role Within the emergence of hematology as a scientific discipline Within the first half of this century, was once instrumental in organising the sector-wide reputation of the Thorndike Memorial Laboratory and the Harvard Medical Unit at Boston City Hospital. Within the first comprehensive biography of Castle, Anand Karnad highlights the golden age of medicine and hematology in Boston. Castle’s early experiments solved the puzzle of pernicious anemia and were the building blocks for a series of experiments on that disease that stand as one of the vital finest examples of clinical research ever conducted.

Castle and his group also made pioneering contributions to hemoglobin physiology, mechanisms of hemolysis, splenic serve as, and sickle cell anemia. Under his leadership, the Thorndike Memorial Laboratory attracted the most productive and the brightest talent, many of whom are present-day leaders on the planet of medicine and science. Intrinsic Factors is the tale of Castle’s life and work.

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